Advancing NanoTechnology in BioMedical Applications
Our Research
The Tang Wei Lab is based in the Department of Pharmacy and Pharmaceutical Sciences at the National University of Singapore (NUS). Our research focuses on leveraging biomaterials to enhance vaccine delivery and immunoengineering strategies for improved therapeutic outcomes in cancer and other health challenges. Our goal is to develop safe, effective technologies that optimize therapy through advanced drug delivery systems. To achieve this, we integrate an interdisciplinary approach, combining biomaterials science, nanomedicine, chemistry, biomedical engineering, and molecular imaging. Current research projects include: developing novel biomaterials and nanoparticles for nucleic acid delivery (mRNA, siRNA, CRISPR-Cas9) in cancer therapy; optimizing delivery technologies for antigens and adjuvants (e.g., STING agonists) to boost vaccine efficacy; integrating biomaterials with cutting-edge approaches in targeted protein degradation (TPD) to enhance immune responses; and engineering living materials or their derivatives to modulate the immunosuppressive tumor microenvironment (TME) by altering cell-cell interactions and tumor metabolism.
Latest News
HIRING! – We are looking for different levels of talents joining our lab, including postdoc research fellows, phd and master students. Reach out if you are passionate about research on vaccine delivery and immunoengineering!
November 2024 – Muye’s review article on Immunometabolic Reprogramming Nanoplatforms has been accepted for publication in Chemical Society Reviews! Congradulations to Muye on this significant achievement!
November 2024 – Drs. Guo Yunqi & Chen Yi-Fang joined the lab as Research Fellows; Wang Tao joined the lab as visiting PhD student. Welcome on board!
August 2024 – Zhang Han & Li Sha joined the lab as PhD students; Ziyan, Siwei, Wenjin, and Yidan joined the lab for their master Capstone Research Projects. Welcome on board!
June 2024 – The Tang Wei Lab was awarded a four-year Singapore National Medical Research Council (NMRC) Open Fund – Individual Research Grant (OF-IRG) (S$ 1.625 Million) to support the research in “Developing Next-Generation Extracellular Vesicle-Based Therapeutic Cancer Vaccines”. Congradulations to the team!
August 2023 – The Tang Wei Lab was awarded a three-year Singapore Ministry of Education (MOE) Tier 2 Grant (S$ 1.124 Million) to support the research in “Developing Pulmonary mRNA Nanovaccines”. Cheers!
August 2023 – Mingyuan joined the lab as PhD student; Haoran and Jingwen joined the lab for their master Capstone Research Projects; Chloe joined the lab for her Final Year Project (FYP). Welcome on board!
June 2023 – Dr. Tang delivered an invited talk at the 13th International NanoMedicine Conference, Sydney, Australia.
May 2023 – Congratulations to our undergraduates Jaryn, Shi Han, and their Team 8A (Drug design, formulation and delivery innovations that lead to better therapeutic outcomes and patient compliance) for winning the Audience’s Choice Prize in the poster competition on the department’s inaugural “SCI-PHI day”. https://pharmacy.nus.edu.sg/newsletter/pharmconnect-0723-a03/
November 2022 – Dr. Yang Zhijuan joined the lab as Research Fellow; Augustine, Jia Wei, Kelly, and Kelvin joined the lab for their undergraduate Final Year Project (FYP). Welcome on board!
September 2022 – Drs. Song Shanliang and Zhao Zhihao joined the lab as Research Fellows. Welcome on board!
August 2022 – Huize and Muye joined the lab as PhD students; Lefei joined the lab for her master Capstone Research Project; Shi Han and Jaryn joined the lab for their undergraduate Student-led Collaborative Innovative Pharmacy Inquiry Project (SCI-PhI). Welcome on board!
July 2022 – The Tang Wei Lab was awarded a three-year Singapore National Medical Research Council (NMRC) Open Fund -Young Individual Research Grant (OF-YIRG) (S$ 0.325 Million) to support the research in “Developing Immunometabolic Nanomodulators for Cancer Immunotherapy”. Cheers!
May 2022 – Dr. Cheng Junjie from the University of Science and Technology of China joined the lab as a visiting scholar. Welcome on board!
January 2022 – Chris and Gwyneth joined the lab for their undergraduate Final Year Project (FYP). Welcome on board!
October 2021 – The Tang Wei Lab @ NUS was officially opened!
